The pathogenesis of atopic eczema
- PMID: 12474608
- DOI: 10.12968/hosp.2002.63.11.1909
The pathogenesis of atopic eczema
Abstract
Atopic eczema is associated with a genetic predisposition to dysregulation of the immune system. T lymphocytes differentiate towards the Th2 type with promotion of immunoglobulin E antibodies. Allergic responses to environmental allergens develop and microbes, including staphylococci and pityrosporum yeasts, may contribute to the inflammatory process.