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Review
. 2002 Dec 19:20 Suppl 4:A28-31.
doi: 10.1016/s0264-410x(02)00384-5.

Tumor-derived exosomes: a new source of tumor rejection antigens

F André  1 , N E C Schartz, N Chaput, C Flament, G Raposo, S Amigorena, E Angevin, L Zitvogel
Affiliations
Review

Tumor-derived exosomes: a new source of tumor rejection antigens

F André et al. Vaccine. .

Abstract

Exosomes are small vesicles released by a broad array of hematopoietic cells. Previous studies showed that exosomes released by antigen loaded dendritic cells induce immune-mediated anti-tumor response in mice. Here, we will describe the biochemical properties of tumor-derived exosomes and, their pre-clinical activity as cancer vaccines.

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