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Review
. 2002 Nov;5(6):918-27.

Aziridines and aziridinium ions in the practical synthesis of pharmaceutical intermediates--a perspective

Vilas H Dahanukar  1 , Ilia A Zavialov
Affiliations
  • PMID: 12478722
Review

Aziridines and aziridinium ions in the practical synthesis of pharmaceutical intermediates--a perspective

Vilas H Dahanukar et al. Curr Opin Drug Discov Devel. 2002 Nov.

Abstract

Recent methods for the synthesis of aziridines and aziridinium ions, the mechanisms of their nucleophilic ring-opening reactions and applications to the practical synthesis of pharmaceutical intermediates are reviewed.

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