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Case Reports
. 2002 Dec;31(12):709-13.
doi: 10.1007/s00256-002-0576-y. Epub 2002 Oct 29.

Atypical form of active melorheostosis and its treatment with bisphosphonate

Judit Donáth  1 , Gyula Poór, Csaba Kiss, Béla Fornet, Harry Genant
Affiliations
Case Reports

Atypical form of active melorheostosis and its treatment with bisphosphonate

Judit Donáth et al. Skeletal Radiol. 2002 Dec.

Abstract

We present the case of a 38-year-old man in whom extensive bilateral melorheostosis was associated with elevated serum alkaline phosphatase, swelling of the right foot and progressive deformity of the left hand, left leg and right foot. Radiography, computed tomography and bone scintigraphy were performed. Following treatment with bisphosphonate (30 mg/day of pamidronate for 6 days) infusion, the pain and swelling of his right foot showed improvement and his elevated serum alkaline phosphatase decreased.

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