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. 1975 May;149(1):89-93.
doi: 10.3181/00379727-149-38749.

The anti-inflammatory actions of tilorone hydrochloride

H Megel, A Raychaudhuri, I Shemano, T H Beaver, L L Thomas

The anti-inflammatory actions of tilorone hydrochloride

H Megel et al. Proc Soc Exp Biol Med. 1975 May.

Abstract

Tilorone suppressed inflammation induced by immune (direct passive Arthus reaction) as well as by non-immune agents (carrageenam-induced paw edema and abscess formation), if the compound is given 24 hr prior to the proinflammatory agonists. The non-immune anti-inflammatory effect is independent of the adrenals. A surprising findings was that total serum hemolytic complement is markedly elevated 24 hr after a single dose of tilorone.

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