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. 1976 Jan 28;31(1):117-9.
doi: 10.1007/BF00270408.

DNA replication patterns of the early S phase from amniotic fluid cells as revealed by a Giemsa staining technique

J T Epplen, T Bauknecht, W Vogel

DNA replication patterns of the early S phase from amniotic fluid cells as revealed by a Giemsa staining technique

J T Epplen et al. Hum Genet. .

Abstract

We report on DNA replication patterns of the early S phase demonstrated by a BUdR/Hoechst (33258)-fluorescence/Giemsa technique. Replication starts in R bands and spreads within 1 hr over the whole chromosome complement with exceptions concerning heterochromatin. The beginning and the duration of replication are discussed.

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