5-methylcytosine in heterochromatic regions of chromosomes in Bovidae
- PMID: 1248820
- DOI: 10.1007/BF00270395
5-methylcytosine in heterochromatic regions of chromosomes in Bovidae
Abstract
The centromeric regions of cattle, goat and sheep chromosomes bind anti-5-MeC as revealed by immunofluorescence technique, indicating concentration of 5-MeC at these heterochromatic regions. The centromere of the submetacentric X of cattle remains nearly unstained and so do the centromeres of the acrocentric X chromosomes in goat and sheep. The short arm of the cattle Y exhibits strong anti-5-MeC binding whereas the tiny Y chromosomes of goat and sheep contain no brightly fluorescent material.
Similar articles
-
5-Methylcytosine in heterochromatic regions of chromosomes: chimpanzee and gorilla compared to the human.Chromosoma. 1975 Sep 15;52(1):59-66. doi: 10.1007/BF00285789. Chromosoma. 1975. PMID: 1175458
-
Immunochemical studies on the 5-methylcytosine content of African green monkey satellite DNA.Cold Spring Harb Symp Quant Biol. 1978;42 Pt 1:397-400. doi: 10.1101/sqb.1978.042.01.041. Cold Spring Harb Symp Quant Biol. 1978. PMID: 98282 No abstract available.
-
Localization of 5-methylcytosine in human metaphase chromosomes by immunoelectron microscopy.Cell. 1976 Dec;9(4 Pt 1):503-9. doi: 10.1016/0092-8674(76)90032-5. Cell. 1976. PMID: 1009572
-
Heterochromatin, satellite DNA, and cell function. Structural DNA of eucaryotes may support and protect genes and aid in speciation.Science. 1971 Dec 17;174(4015):1200-9. doi: 10.1126/science.174.4015.1200. Science. 1971. PMID: 4943851 Review.
-
[Heterochromatic regions of chromosomes: structure and function].Zh Obshch Biol. 1977 Sep-Oct;38(5):735-67. Zh Obshch Biol. 1977. PMID: 73281 Review. Russian. No abstract available.
Cited by
-
New sites of methylcytosine-rich DNA detected on metaphase chromosomes.Hum Genet. 1994 Dec;94(6):684-92. doi: 10.1007/BF00206964. Hum Genet. 1994. PMID: 7989044
-
Hypermethylation of human DNA sequences in embryonal carcinoma cells and somatic tissues but not in sperm.Nucleic Acids Res. 1987 Nov 25;15(22):9429-49. doi: 10.1093/nar/15.22.9429. Nucleic Acids Res. 1987. PMID: 2825135 Free PMC article.
-
Distribution of 5-methylcytosine-rich regions in the metaphase chromosomes of Vicia faba.Chromosome Res. 1996 Feb;4(2):141-6. doi: 10.1007/BF02259707. Chromosome Res. 1996. PMID: 8785608
-
5-methylcytosine in the DNA of the polytene chromosomes of the diptera Sciara coprophila, Drosophila melanogaster and D. persimilis.Chromosoma. 1980;79(2):225-39. doi: 10.1007/BF01175188. Chromosoma. 1980. PMID: 6772415
-
Pattern of undermethylation of the major satellite DNA of mouse sperm.Nucleic Acids Res. 1985 Jun 11;13(11):3969-78. doi: 10.1093/nar/13.11.3969. Nucleic Acids Res. 1985. PMID: 2989780 Free PMC article.