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. 1976 Jan 28;31(1):21-6.
doi: 10.1007/BF00270395.

5-methylcytosine in heterochromatic regions of chromosomes in Bovidae

W Schnedl, B F Erlanger, O J Miller

5-methylcytosine in heterochromatic regions of chromosomes in Bovidae

W Schnedl et al. Hum Genet. .

Abstract

The centromeric regions of cattle, goat and sheep chromosomes bind anti-5-MeC as revealed by immunofluorescence technique, indicating concentration of 5-MeC at these heterochromatic regions. The centromere of the submetacentric X of cattle remains nearly unstained and so do the centromeres of the acrocentric X chromosomes in goat and sheep. The short arm of the cattle Y exhibits strong anti-5-MeC binding whereas the tiny Y chromosomes of goat and sheep contain no brightly fluorescent material.

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