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. 2003 Jan;10(1):2-3.
doi: 10.1038/nsb0103-2.

Moving across membranes

Elaine A Neale

Moving across membranes

Elaine A Neale. Nat Struct Biol. 2003 Jan.

Erratum in

  • Nat Struct Biol. 2003 Feb;10(2):146

Abstract

Protein toxins are known to translocate through intracellular membranes to reach their cytosolic targets. Results from studies with botulinum neurotoxin suggest that the toxin heavy chain functions as both a channel and a chaperone for translocation of the catalytically active light chain.

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