Review
doi: 10.1016/s0962-8924(02)02400-5.
Kinesin motors and disease
Affiliations
- PMID: 12495847
- DOI: 10.1016/s0962-8924(02)02400-5
Item in Clipboard
Review
Kinesin motors and disease
Trends Cell Biol.
2002 Dec.
Abstract
Kinesins are motor proteins that move cargoes such as vesicles, organelles and chromosomes along microtubules. They are best known for their role in axonal transport and in mitosis. There is a diverse family of kinesins, members of which differ in composition and functions. Roles of kinesins in diseases typically involve defective transport of cell components, transport of pathogens, or cell division.
Similar articles
-
One axon, many kinesins: What's the logic?J Neurocytol. 2000 Nov-Dec;29(11-12):799-818. doi: 10.1023/a:1010943424272. J Neurocytol. 2000. PMID: 11466472 Review.
-
The UNC-104/KIF1 family of kinesins.Curr Opin Cell Biol. 2001 Feb;13(1):36-40. doi: 10.1016/s0955-0674(00)00171-x. Curr Opin Cell Biol. 2001. PMID: 11163131 Review.
-
Kinesin assembly and movement in cells.Annu Rev Biophys. 2011;40:267-88. doi: 10.1146/annurev-biophys-042910-155310. Annu Rev Biophys. 2011. PMID: 21332353 Review.
-
Conversion of Unc104/KIF1A kinesin into a processive motor after dimerization.Science. 2002 Sep 27;297(5590):2263-7. doi: 10.1126/science.1073386. Science. 2002. PMID: 12351789
-
Trafficking of signaling modules by kinesin motors.J Cell Sci. 2003 Jun 1;116(Pt 11):2125-35. doi: 10.1242/jcs.00488. J Cell Sci. 2003. PMID: 12730289 Review.
Cited by
-
Molecular characterization of a KIF3A-like kinesin gene in the testis of the Chinese fire-bellied newt Cynops orientalis.Mol Biol Rep. 2012 Apr;39(4):4207-14. doi: 10.1007/s11033-011-1206-3. Epub 2011 Jul 20. Mol Biol Rep. 2012. PMID: 21773941
-
The mechanism of kinesin inhibition by kinesin-binding protein.Elife. 2020 Nov 30;9:e61481. doi: 10.7554/eLife.61481. Elife. 2020. PMID: 33252036 Free PMC article.
-
Molecular interaction of α-synuclein with tubulin influences on the polymerization of microtubule in vitro and structure of microtubule in cells.Mol Biol Rep. 2010 Oct;37(7):3183-92. doi: 10.1007/s11033-009-9899-2. Epub 2009 Oct 14. Mol Biol Rep. 2010. PMID: 19826908
-
Structural basis for isoform-specific kinesin-1 recognition of Y-acidic cargo adaptors.Elife. 2018 Oct 15;7:e38362. doi: 10.7554/eLife.38362. Elife. 2018. PMID: 30320553 Free PMC article.
-
Coordination of autophagosome-lysosome fusion and transport by a Klp98A-Rab14 complex in Drosophila.J Cell Sci. 2016 Mar 1;129(5):971-82. doi: 10.1242/jcs.175224. Epub 2016 Jan 13. J Cell Sci. 2016. PMID: 26763909 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
