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Review
. 2002 Dec;9(12):1270-3.
doi: 10.1016/s1074-5521(02)00291-0.

One step closer to a sweet conclusion

Stephen G Withers  1 , Warren W Wakarchuk, Natalie C J Strynadka
Affiliations
Review

One step closer to a sweet conclusion

Stephen G Withers et al. Chem Biol. 2002 Dec.

Abstract

OtsA is required for the biosynthesis of trehalose, a nonreducing disaccharide that is important for bacterial survival and stress responses. In this issue of Chemistry & Biology, the structure of OtsA is uncovered and reveals an unexpected relationship between the enzyme's structure and function.

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