Controversies in urinary iodine determinations
- PMID: 12498990
- PMCID: PMC3637997
- DOI: 10.1016/s0009-9120(02)00406-x
Controversies in urinary iodine determinations
Abstract
Iodine deficiency (ID) is associated with increased prevalence of goiter, increased risk for neurodevelopmental disorders, and is the world's leading cause of intellectual deficits. Iodine nutritional status of a population is assessed by measurements of urinary iodine concentrations which are also used to define, indicate, survey and monitor iodine deficiency and consequently its treatment. Several methods are available for urinary iodine determination. Discussed here are some of the limitations and controversies related to urinary iodine determinations, and recent findings with emphasis on measurements of urinary iodine concentrations in children and during pregnancy.
Copyright 2002 The Canadian Society of Clinical Chemists
References
-
- Hollowell JG, Staehling NW, Hannon WH, et al. Iodine nutrition in the United States. Trends and public health implications: iodine excretion data from National Health and Nutrition Examination Surveys I and III (1971–1974 and 1988–1994) J Clin Endocrinol Metab. 1998;83(10):3401–8. - PubMed
-
- World Health Organization Nutrition Unit. Indicators for assessing iodine deficiency disorders (IDD), and their control through salt iodization. Geneva: WHO; 1994. p. 36.
-
- Schwab SJ, Christensen RL, Dougherty K, Klahr S. Quantitation of proteinuria by the use of protein-to-creatinine ratios in single urine samples. Arch Intern Med. 1987;147(5):943–4. - PubMed
-
- Chitalia VC, Kothari J, Wells EJ, et al. Cost-benefit analysis and prediction of 24-hour proteinuria from the spot urine protein-creatinine ratio. Clin Nephrol. 2001;55(6):436–47. - PubMed
-
- Bourdoux P. Measurement of iodine in the assessment of iodine deficiency. IDD Newsletter. 1988;4:8–12.
Publication types
MeSH terms
Substances
Grants and funding
LinkOut - more resources
Full Text Sources