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. 2003 Jan;47(1):416-7.
doi: 10.1128/AAC.47.1.416-417.2003.

In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs

Luis Alcalá  1 , María Jesús Ruiz-Serrano, Cristina Pérez-Fernández Turégano, Darío García De Viedma, Marisol Díaz-Infantes, Mercedes Marín-Arriaza, Emilio Bouza
Affiliations

In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs

Luis Alcalá et al. Antimicrob Agents Chemother. 2003 Jan.

Abstract

We evaluated 117 isolates of Mycobacterium tuberculosis for susceptibility to linezolid by the proportion and E-test methods. Linezolid showed high in vitro activity, with all the strains inhibited by <or=1 microg of the drug per ml. E-test MICs were at least 4 dilutions lower than their equivalents by the standard proportion method.

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