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Review
. 2003 Jan;56(1):17-25.
doi: 10.1136/jcp.56.1.17.

acp Best Practice No 168. The investigation and management of obesity

M Labib  1
Affiliations
Review

acp Best Practice No 168. The investigation and management of obesity

M Labib. J Clin Pathol. 2003 Jan.

Abstract

Obesity is a chronic condition characterised by an excess of body fat. It is a complex disorder of appetite regulation and energy metabolism controlled by specific biological factors. In the past 10 years, great progress has been made in the scientific understanding of the pathophysiology of obesity and the interactions between genetic predisposition to weight gain and the environment. This article will review the current understanding of the pathophysiology and the approach to the investigation and management of obesity.

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References

    1. World Health Organisation. Obesity: preventing and managing the global epidemic. Report of a World Health Organisation consultation on obesity. Geneva: World Health Organisation, 1998. - PubMed
    1. McKeigue PM, Shah B, Marmot MG. Relation of central obesity and insulin resistance with high diabetes prevalence and cardiovascular risk in South Asians. Lancet 1991;337:382–6. - PubMed
    1. Han TS, van Leer EM, Seidell JC, et al. Waist circumference action levels in identification of cardiovascular risk factors: prevalence study in a random sample. BMJ 1995;311:1401–5. - PMC - PubMed
    1. Erens B, Primatesta P. Health survey for England: cardiovascular disease. London: The Stationery Office, 1998.
    1. Rudolf M, Sahota P, Barth J, et al. Increasing prevalence of obesity in primary school children: cohort study. BMJ 2001;322:1094–5. - PMC - PubMed

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