Detection of glaucomatous visual field defect by nonconventional perimetry

Abstract

Purpose: To report the correlations among Humphrey Field Analyzer 750 (HFA), high-pass resolution perimetry (HRP), and frequency-doubling technology (FDT) perimetry in glaucoma patients and ocular hypertensive patients.

Design: Cross-sectional study.

Methods: Eighty-two eyes of 82 consecutive patients with primary open-angle glaucoma (POAG) or ocular hypertension were included in this study. One eye of each patient was randomly selected for data analysis. Visual fields were assessed by HFA, HRP, and FDT perimetry. HRP global deviation (HRP-GD), HRP local deviation (HRP-LD), FDT-mean deviation (FDT-MD), and FDT-pattern standard deviation (FDT-PSD) were considered for the analysis. Clinical agreement between HRP and FDT was evaluated. All data were analyzed by Pearson r coefficient when the distribution of the data was normal and by Spearman coefficient correlation when the distribution of the data was not normal. A P <.05 was considered statistically significant.

Results: Fifty-two eyes (52 patients) were classified as glaucoma and 30 eyes (30 patients) as ocular hypertension. In the entire group, a significant (P >.001) correlation was found between the HFA indices and those of either HRP or FDT. A significant (P <.001) correlation was found between HRP-GD and FDT-MD as well as between HRP-LD and FDT-PSD. In 14% of the glaucomatous patients and in 33% of the subjects with ocular hypertension, FDT and HRP showed different clinical features.

Conclusions: Our data suggest that FDT and HRP are useful for detection of early glaucomatous visual field damage.