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. 1976 Jan;3(1):205-18.
doi: 10.1093/nar/3.1.205.

Protonated polynucleotide structures. 18. Interaction of oligocytidylates with poly (G)

B L Haas, W Guschlbauer
Free PMC article

Protonated polynucleotide structures. 18. Interaction of oligocytidylates with poly (G)

B L Haas et al. Nucleic Acids Res. 1976 Jan.
Free PMC article

Abstract

The faculty for and degree of oligo(C)-poly(G) interaction is described as an essentially chain length - sensitive phenomenon. At neutral pH under suitable experimental conditions, oligocytidylates of chain length greater than four associate with poly(G) to form double-stranded structures, as does poly(C). The extent of complex formation increases with degree of polymerization. The complex at acid pH is shown to be triple-stranded, of stoicheometry 2C/1G. The observation of a 2G/1C artifact is discussed.

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