doi: 10.1126/science.1251192.
Proviral DNA of Moloney leukemia virus: purification and visualization
- PMID: 1251192
- DOI: 10.1126/science.1251192
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Proviral DNA of Moloney leukemia virus: purification and visualization
Science.
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Abstract
Closed-circular proviral DNA of Moloney leukemia virus has been purified from a 10(7) excess of cellular and mitochondrial DNA. The DNA can be visualized in the electron microscope and has the contour length of a molecule with a moleculecular weight of about 5.5 + 10(6). Electron microscopic observation of a hybrid between viral RNA and this circular DNA confirms the viral origin of this molecule.
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