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Review
. 2003 Feb;15(1):67-72.
doi: 10.1016/s0955-0674(02)00005-4.

Cell polarity: Par6, aPKC and cytoskeletal crosstalk

Sandrine Etienne-Manneville  1 , Alan Hall
Affiliations
Review

Cell polarity: Par6, aPKC and cytoskeletal crosstalk

Sandrine Etienne-Manneville et al. Curr Opin Cell Biol. 2003 Feb.

Abstract

Par6 and atypical protein kinase C are key players in the establishment of cell polarity. First discovered in Caenorhabditis elegans, the function of this protein complex is conserved in all multicellular organisms. Recent work is beginning to throw light on how it converts information generated by extracellular cues into intracellular asymmetry.

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