Juvenile Cushing syndrome manifested primarily by growth failure
- PMID: 1251826
- DOI: 10.1001/archpedi.1976.02120030090018
Juvenile Cushing syndrome manifested primarily by growth failure
Abstract
An 11-year-old boy had Cushing syndrome with profound growth retardation, but without the associated clinical characteristics of the disease. Treatment with growth hormone failed to promote growth, suggesting that growth failure in the presence of excess glucocorticoids is due to peripheral tissue resistance to growth hormone rather than to impairment of growth hormone secretion.