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. 2003 Jan 1;31(1):133-7.
doi: 10.1093/nar/gkg053.

WormBase: a cross-species database for comparative genomics

Todd W Harris  1 , Raymond Lee, Erich Schwarz, Keith Bradnam, Daniel Lawson, Wen Chen, Darin Blasier, Eimear Kenny, Fiona Cunningham, Ranjana Kishore, Juancarlos Chan, Hans-Michael Muller, Andrei Petcherski, Gudmundur Thorisson, Allen Day, Tamberlyn Bieri, Anthony Rogers, Chao-Kung Chen, John Spieth, Paul Sternberg, Richard Durbin, Lincoln D Stein
Affiliations

WormBase: a cross-species database for comparative genomics

Todd W Harris et al. Nucleic Acids Res. .

Abstract

WormBase (http://www.wormbase.org/) is a web-accessible central data repository for information about Caenorhabditis elegans and related nematodes. The past two years have seen a significant expansion in the biological scope of WormBase, including the integration of large-scale, genome-wide data sets, the inclusion of genome sequence and gene predictions from related species and active literature curation. This expansion of data has also driven the development and refinement of user interfaces and operability, including a new Genome Browser, new searches and facilities for data access and the inclusion of extensive documentation. These advances have expanded WormBase beyond the obvious target audience of C. elegans researchers, to include researchers wishing to explore problems in functional and comparative genomics within the context of a powerful genetic system.

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Figures

Figure 1
Figure 1
An expanded view of the Genome Browser, display a variety of features including genes, alignments with C. briggsae, ESTs and RNAi experiments.
Figure 1
Figure 1
A typical page for an RNAi experiment. QuickTime movies of many results help to illustrate developmental timing defects.
See this image and copyright information in PMC

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