Controlling calcium entry
- PMID: 12526803
- DOI: 10.1016/s0092-8674(02)01197-2
Controlling calcium entry
Abstract
Ca(2+) enters cells through an assortment of Ca(2+)-permeable channels that respond to different stimuli and couple to different cellular responses. Several different Ca(2+) entry pathways can be activated by receptors that stimulate phospholipase C (PLC). Both limbs of this signaling pathway (IP(3) and diacylglycerol), PLC itself, and its substrate (PIP(2)) contribute to the coordinate regulation of these Ca(2+) entry pathways.
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