Antigen-driven clonal T cell expansion in disorders of hematopoiesis
- PMID: 12531218
- DOI: 10.1016/s0145-2126(02)00270-9
Antigen-driven clonal T cell expansion in disorders of hematopoiesis
Abstract
Patients with myelodysplastic syndrome, aplastic anemia, and LGL leukemia may have overlapping clinical features. This commentary highlights a possible common pathogenetic mechanism of antigen-driven cytotoxic T lymphocytes mediating hematopoietic failure.
Comment on
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Determination of T-cell receptors of clonal CD8-positive T-cells in myelodysplastic syndrome with erythroid hypoplasia.Leuk Res. 2003 Apr;27(4):305-12. doi: 10.1016/s0145-2126(02)00173-x. Leuk Res. 2003. PMID: 12531221
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