Review
[Roles of alpha-2 adrenoceptor in prefrontal cortical cognitive functions]
[Article in
Chinese]
Affiliations
- PMID: 12532843
Item in Clipboard
Review
[Roles of alpha-2 adrenoceptor in prefrontal cortical cognitive functions]
[Article in
Chinese]
Sheng Li Ke Xue Jin Zhan.
1999 Jan.
Abstract
Studies in non-human primates have demonstrated that norepinephrine can improve, through actions at postsynaptical alpha-2A adrenoceptors, cognitive functions of the prefrontal cortex, such as attentional regulation, working memory and response inhibition. Several psychiatric disorders, including attention-deficit hyperactivity disorder (ADHD), show prominent syndromes seen in cognitive deficits of the prefrontal cortex. These basic studies help develop novel pharmacotherapies for psychiatric disorders such as ADHD.
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