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. 2003;2003(1):CD003247.
doi: 10.1002/14651858.CD003247.

Interventions for treating placental abruption

J P Neilson  1
Affiliations

Interventions for treating placental abruption

J P Neilson. Cochrane Database Syst Rev. 2003.

Abstract

Background: Placental abruption is an important cause of maternal and fetal mortality and morbidity.

Objectives: To assess the effectiveness and safety of any intervention for the care of women and/or their babies following a diagnosis of placental abruption.

Search strategy: Comprehensive electronic search of the Cochrane Pregnancy and Childbirth trials register. Date of last search: October 2002.

Selection criteria: Randomised and 'quasi-randomised' trials that report clinically meaningful outcomes and present results on an intention to treat basis.

Data collection and analysis: If eligible trials were to be identified, data will be extracted, unblinded, by the reviewer from all studies.

Main results: No studies that met the inclusion criteria were identified.

Reviewer's conclusions: The clinical management of placental abruption has to rely on knowledge other than that obtained through randomised clinical trials.

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Conflict of interest statement

None known.

References

References to studies excluded from this review

Daftary 1983 {published data only}
    1. Daftary SN, Aggarwala V. Antagosan in abruptio‐placentae. Current Therapeutic Research, Clinical and Experimental 1983;34:974‐81.
Hall 1972 {published data only}
    1. Hall MH. Folic acid deficiency and abruptio placentae. Journal of Obstetrics and Gynaecology of the British Commonwealth 1972;79:222‐5. - PubMed
Okonofua 1985 {published data only}
    1. Okonofua FE, Olatunbosun OA. Cesarean versus vaginal delivery in abruptio placentae associated with live fetuses. International Journal of Gynecology & Obstetrics 1985;23:471‐4. - PubMed

References to ongoing studies

El‐Sayed 2006 {published data only}
    1. El‐Sayed YY. Randomized, double blind trial of magnesium sulfate tocolysis versus intravenous saline for suspected placental abruption (ongoing trial). ClinicalTrials.gov (http://clinicaltrials.gov/) (accessed 21 March 2006).

Additional references

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Ananth 2001a
    1. Ananth CV, Wilcox AJ. Placental abruption and perinatal mortality in the United States. American Journal of Epidemiology 2001;153:332‐7. - PubMed
Ananth 2001b
    1. Ananth CV, Smulian JC, Demissie K, Vintzileos AM, Knuppel RA. Placental abruption among singleton and twin births in the United States: risk factor profiles. American Journal of Epidemiology 2001;153:771‐8. - PubMed
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