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. 2001 Aug 28;26(4):343-4.

[Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy]

[Article in Chinese]
X P Zhu  1 , Z G Zhou
Affiliations
  • PMID: 12536730

[Clinical observation of combined therapeutic effect of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy]

[Article in Chinese]
X P Zhu et al. Hunan Yi Ke Da Xue Xue Bao. .

Abstract

Objective: To observe the clinical effect of combined treatment of prostaglandin E1 and mecobalamin on diabetic peripheral neuropathy(DPN).

Methods: Seventy two patients of DPN were divided into 3 groups, they were given the drug of prostaglandin E1 (PGE1), mecobalamin, PGE1 plus mecobalamin (combined therapeutic group) and compared the therapeutic effects respectively.

Results: The improvement of DPN symptoms and nerve conducting speeds of combined therapeutic group was obviously better than that of the single PGE1 group or mecobalamin group(P < 0.01).

Conclusion: Combined therapy of PGE1 and mecobalamin is better than each of single drug for improvement of DPN symptoms.

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