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. 2002 Dec 21:(24):3024-5.
doi: 10.1039/b207664k.

Direct organocatalytic aldol reactions in buffered aqueous media

Armando Córdova  1 , Wolfgang Notz, Carlos F Barbas 3rd
Affiliations

Direct organocatalytic aldol reactions in buffered aqueous media

Armando Córdova et al. Chem Commun (Camb). .

Abstract

Organocatalytic cross-aldol reactions catalyzed by cyclic secondary amines in aqueous media provide a direct route to a variety of aldols including carbohydrate derivatives and may warrant consideration as a prebiotic route to sugars.

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