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. 2003 Feb;47(2):804-8.
doi: 10.1128/AAC.47.2.804-808.2003.

Molecular epidemiology of penicillin-resistant and ciprofloxacin-resistant Streptococcus pneumoniae in Canada

Kimberly A Nichol  1 , George G Zhanel, Daryl J Hoban
Affiliations

Molecular epidemiology of penicillin-resistant and ciprofloxacin-resistant Streptococcus pneumoniae in Canada

Kimberly A Nichol et al. Antimicrob Agents Chemother. 2003 Feb.

Abstract

Eighty-nine penicillin- and ciprofloxacin-resistant Streptococcus pneumoniae isolates were evaluated by serotyping and pulsed-field gel electrophoresis. Although penicillin-resistant isolates demonstrated considerable homogeneity, resistance to ciprofloxacin did not correlate with a reduction in genotypic variability. These results suggest that, unlike that of penicillin resistance, the spread of S. pneumoniae ciprofloxacin resistance in Canada is currently not attributable to clonal dissemination.

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