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Review
. 2003 Jan;31(1 Suppl):S94-6.
doi: 10.1097/00003246-200301001-00013.

Recombinant human activated protein C in sepsis: inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials

Peter Q Eichacker  1 , Charles Natanson
Affiliations
Review

Recombinant human activated protein C in sepsis: inconsistent trial results, an unclear mechanism of action, and safety concerns resulted in labeling restrictions and the need for phase IV trials

Peter Q Eichacker et al. Crit Care Med. 2003 Jan.
No abstract available

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Comment in

  • Pro/Con debate of activated protein C in severe sepsis.
    Joore JC, van Leeuwen HJ, Meulenbelt J, Tobé TJ, Fijen JW. Joore JC, et al. Crit Care Med. 2003 Aug;31(8):2249. doi: 10.1097/01.CCM.0000087327.59341.18. Crit Care Med. 2003. PMID: 12973192 No abstract available.
  • Recombinant activated protein C.
    Fuerst W. Fuerst W. Crit Care Med. 2004 Jan;32(1):311-2. doi: 10.1097/01.CCM.0000104932.57061.AD. Crit Care Med. 2004. PMID: 14707611 No abstract available.

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