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Review
. 2001 Jan;32(1):35-8.

[Calcium dependent synaptic plasticity]

[Article in Chinese]
Y Dou  1 , J Yan, Y Y Wu, R Y Cui, C L Lu
Affiliations
  • PMID: 12545775
Review

[Calcium dependent synaptic plasticity]

[Article in Chinese]
Y Dou et al. Sheng Li Ke Xue Jin Zhan. 2001 Jan.

Abstract

Recent work shows that the intracellular free Ca2+ concentrations ([Ca2+]i) of the presynaptic and postsynaptic neurons play crucial signaling roles in short- and long-term synaptic plasticity. Residual [Ca2+]i followed conditioning stimulation may cause short-term synaptic enhancement. Presynaptic [Ca2+]i could influence the replacing of presynaptic depressed vesicles, as well as encode the precise relative timing of presynaptic input and postsynaptic activity and generate long-term synaptic modification of opposite polarity(LTP or LTD).

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