Review
doi: 10.1042/bst0310162.
AMP-activated protein kinase, super metabolic regulator
Affiliations
- PMID: 12546677
- DOI: 10.1042/bst0310162
Item in Clipboard
Review
AMP-activated protein kinase, super metabolic regulator
Biochem Soc Trans.
2003 Feb.
Abstract
The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well as controlling gene expression.
Similar articles
-
[Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases].Med Sci (Paris). 2006 Apr;22(4):381-8. doi: 10.1051/medsci/2006224381. Med Sci (Paris). 2006. PMID: 16597407 Review. French.
-
Targeting AMP-activated protein kinase as a novel therapeutic approach for the treatment of metabolic disorders.Diabetes Metab. 2007 Dec;33(6):395-402. doi: 10.1016/j.diabet.2007.10.004. Epub 2007 Nov 7. Diabetes Metab. 2007. PMID: 17997341 Review.
-
Role of AMP-activated protein kinase in the control of appetite.J Neuroendocrinol. 2008 Jul;20(7):942-51. doi: 10.1111/j.1365-2826.2008.01745.x. Epub 2008 Apr 28. J Neuroendocrinol. 2008. PMID: 18445126 Free PMC article. Review.
-
A molecular approach to the concerted action of kinases involved in energy homoeostasis.Biochem Soc Trans. 2003 Feb;31(Pt 1):169-74. doi: 10.1042/bst0310169. Biochem Soc Trans. 2003. PMID: 12546678 Review.
-
AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart.Biochem Soc Trans. 2003 Feb;31(Pt 1):207-12. doi: 10.1042/bst0310207. Biochem Soc Trans. 2003. PMID: 12546686 Review.
Cited by
-
PARP-1 modulation of mTOR signaling in response to a DNA alkylating agent.PLoS One. 2012;7(10):e47978. doi: 10.1371/journal.pone.0047978. Epub 2012 Oct 24. PLoS One. 2012. PMID: 23110147 Free PMC article.
-
Metformin Prevents Tumor Cell Growth and Invasion of Human Hormone Receptor-Positive Breast Cancer (HR+ BC) Cells via FOXA1 Inhibition.Int J Mol Sci. 2024 Jul 8;25(13):7494. doi: 10.3390/ijms25137494. Int J Mol Sci. 2024. PMID: 39000600 Free PMC article.
-
CTRP13 Mitigates Endothelial Cell Ferroptosis via the AMPK/KLF4 Pathway: Implications for Atherosclerosis Protection.Med Sci Monit. 2024 Jan 26;30:e942733. doi: 10.12659/MSM.942733. Med Sci Monit. 2024. PMID: 38273650 Free PMC article.
-
Protective effects of AMP-activated protein kinase in the cardiovascular system.J Cell Mol Med. 2010 Nov;14(11):2604-13. doi: 10.1111/j.1582-4934.2010.01179.x. J Cell Mol Med. 2010. PMID: 20874722 Free PMC article. Review.
-
Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain.J Physiol. 2006 Jul 1;574(Pt 1):85-93. doi: 10.1113/jphysiol.2006.110122. Epub 2006 May 11. J Physiol. 2006. PMID: 16690704 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
