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Review
. 2003 Feb;24(2):97-101.

Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline

Jing-Shan Shi  1 , Jun-Xian Yu, Xiu-Ping Chen, Rui-Xia Xu
Affiliations
  • PMID: 12546715
Free article
Review

Pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline

Jing-Shan Shi et al. Acta Pharmacol Sin. 2003 Feb.
Free article

Abstract

The pharmacological actions of Uncaria alkaloids, rhynchophylline and isorhynchophylline extracted from Uncaria rhynchophylla Miq Jacks were reviewed. The alkaloids mainly act on cardiovascular system and central nervous system including the hypotension, brachycardia, antiarrhythmia, and protection of cerebral ischemia and sedation. The active mechanisms were related to blocking of calcium channel, opening of potassium channel, and regulating of nerve transmitters transport and metabolism, etc.

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