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. 1976 Jan;17(1):38-45.

Measurement of squalene in human tissues and plasma: validation and application

G C Liu, E H Ahrens Jr, P H Schreibman, J R Crouse
  • PMID: 1255019
Free article

Measurement of squalene in human tissues and plasma: validation and application

G C Liu et al. J Lipid Res. 1976 Jan.
Free article

Abstract

A method is described for accurate and reproducible measurement of squalene in plasma, feces, urine, bile, and tissue that depends on isolation by alumina column chromatography after mild saponification and on measurement by gas-liquid chromatography. Recoveries from all tissues exceeded 80% and from plasma 96%; losses were accurately corrected by appropriate additions of squalene as an overall recovery standard.

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