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Review
. 2002;23(6):577-81.

Primary small-cell carcinoma of the endometrium: clinicopathological study of a case and review of the literature

M Varras  1 , Ch Akrivis, A Demou, G Hadjopoulos, S Stefanaki, N Antoniou
Affiliations
  • PMID: 12556112
Review

Primary small-cell carcinoma of the endometrium: clinicopathological study of a case and review of the literature

M Varras et al. Eur J Gynaecol Oncol. 2002.

Abstract

Background: Small-cell carcinomas are almost always primary in the lungs and are highly malignant. These tumors may also occur in the female genital tract. However, primary small-cell carcinoma of the endometrium is extremely rare with very few cases reported in the English literature. This tumor may exhibit evidence of neuroendocrine differentiation and has a high propensity for systemic spread and poor prognosis.

Case: A 55-year-old postmenopausal woman with primary small-cell carcinoma of the endometrium, FIGO stage Ib, underwent total abdominal hysterectomy with bilateral salpingo-oophorectomy and sampling node biopsies of the parametrial spaces, followed by adjuvant combined chemotherapy.

Conclusion: A case of small-cell carcinoma of the endometrium, is reported and its clinical, histological and immunohistochemical features are discussed.

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