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. 2003 Feb 6;5(3):301-4.
doi: 10.1021/ol027266q.

Regioselective palladium-catalyzed arylation of 3-carboalkoxy furan and thiophene

Affiliations

Regioselective palladium-catalyzed arylation of 3-carboalkoxy furan and thiophene

Bobby Glover et al. Org Lett. .

Abstract

[reaction: see text] The regioselective palladium(0)-catalyzed arylation of 3-furoate and 3-thiophenecarboxylate esters with aryl bromides is described. Conditions were developed that allow for the selective synthesis of either 2-aryl or 5-aryl products.

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