The relationship between diabetes and pancreatic cancer
- PMID: 12556242
- PMCID: PMC149418
- DOI: 10.1186/1476-4598-2-4
The relationship between diabetes and pancreatic cancer
Abstract
About 80% of pancreatic cancer patients have glucose intolerance or frank diabetes. This observation has led to the following two hypotheses: i. pancreatic cancer causes the associated diabetes and ii. the conditions associated with diabetes promote the development of pancreatic cancer. Evidence supporting both hypotheses has been accumulated in previous studies. This article reviews these studies, especially those that have been conducted recently.
References
-
- Nix GA, Schmitz PI, Wilson JH, van Blankenstein M, Groeneveld CF, Hofwijk R. Carcinoma of the head of the pancreas. Therapeutic implications of endoscopic retrograde cholangiopancreatography findings. Gastroenterology. 1984;87:37–43. - PubMed
-
- Gudjonsson B. Cancer of the pancreas. 50 years of surgery. Cancer. 1987;60:2284–2303. - PubMed
-
- Permert J, Ihse I, Jorfeldt L, von Schenck H, Arnqvist HJ, Larsson J. Pancreatic cancer is associated with impaired glucose metabolism. Eur J Surg. 1993;159:101–107. - PubMed
-
- Schwarts SS, Zeidler A, Moossa AR, Kuku SF, Rubenstein AH. A prospective study of glucose tolerance, insulin, C-peptide, and glucagon responses in patients with pancreatic carcinoma. Dig Dis. 1978;23:1107–1114. - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
