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Review
. 2003 Jan;3(1):1-3.
doi: 10.1016/s1535-6108(03)00002-3.

Initiation of angiogenic Kaposi's sarcoma lesions

Gary S Hayward  1
Affiliations
Free article
Review

Initiation of angiogenic Kaposi's sarcoma lesions

Gary S Hayward. Cancer Cell. 2003 Jan.
Free article

Abstract

A new mouse model reported in this issue of Cancer Cell implies that VEGF/KDR-mediated paracrine effects induced by the lytic cycle vGPCR signaling protein encoded by human Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) may be involved in promoting the proliferation of the KSHV latently infected spindle endothelial cells of Kaposi's sarcoma.

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