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Case Reports
. 2002 Dec;50(12):530-2.
doi: 10.1007/BF02913169.

Paravalvular leakage causing hemolytic anemia at 8-9 years after mitral valve replacement

Yoshio Misawa  1 , Hiroaki Konishi, Tsutomu Saito, Katsuo Fuse
Affiliations
Case Reports

Paravalvular leakage causing hemolytic anemia at 8-9 years after mitral valve replacement

Yoshio Misawa et al. Jpn J Thorac Cardiovasc Surg. 2002 Dec.

Abstract

We report two similar cases of women, aged 52 and 71 years, who developed shortness of breath or easy fatigability at 8-9 years after mitral valve replacement of the mitral valve in each patient, the echocardiographic study revealed paravalvular leakage. Previous examination before the appearance of symptoms had revealed a well-functioned prosthetic valve, and no hematological abnormality had been detected. The hemoglobin levels at admission were 6.4 and 6.6 g/dl, and their serum lactate dehydrogenase levels were 5218 and 4608 mU/ml. Each successfully underwent another valve replacement, and after surgery, the hemolytic anemia and the symptoms disappeared.

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