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. 1975 Aug 20;401(2):256-64.
doi: 10.1016/0005-2736(75)90309-0.

Calcium uptake by placental plasma membrane vesicles

Y Shami, H H Messer, D H Copp

Calcium uptake by placental plasma membrane vesicles

Y Shami et al. Biochim Biophys Acta. .

Abstract

The placental plasma membrane vesicles are capable of accumulating up to 190 mM Ca2+. This is 24-fold higher than the external Ca2+ concentration. This process is dependent on ATP hydrolysis by the placental Ca2+-ATPase. The Pi/Ca ratio is dependent on the external Ca2+ concentration, and reaches the value of 2 at 10 mM Ca2+. Phosphate (5 mM) can double Ca2+ uptake when measured in the presence of 5 mM Ca2+. Mg2+ increased Ca2+ uptake only at low Ca2+ concentrations, and had no significant effect at 5 mM Ca2+.

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