Is alloantigen expression by host epithelium required for acute graft-versus-host disease?

Comment

Marco Mielcarek et al. Nat Med. 2003 Feb.

. 2003 Feb;9(2):150-1; author reply 151.

doi: 10.1038/nm0203-150.

No abstract available

Comment on

Acute graft-versus-host disease does not require alloantigen expression on host epithelium.
Teshima T, Ordemann R, Reddy P, Gagin S, Liu C, Cooke KR, Ferrara JL. Teshima T, et al. Nat Med. 2002 Jun;8(6):575-81. doi: 10.1038/nm0602-575. Nat Med. 2002. PMID: 12042807

Acute graft-versus-host disease does not require alloantigen expression on host epithelium.
Teshima T, Ordemann R, Reddy P, Gagin S, Liu C, Cooke KR, Ferrara JL. Teshima T, et al. Nat Med. 2002 Jun;8(6):575-81. doi: 10.1038/nm0602-575. Nat Med. 2002. PMID: 12042807
A crucial role for antigen-presenting cells and alloantigen expression in graft-versus-leukemia responses.
Reddy P, Maeda Y, Liu C, Krijanovski OI, Korngold R, Ferrara JL. Reddy P, et al. Nat Med. 2005 Nov;11(11):1244-9. doi: 10.1038/nm1309. Epub 2005 Oct 16. Nat Med. 2005. PMID: 16227991
GVHD prevention: an ounce is better than a pound.
Reddy P, Socié G, Cutler C, Weisdorf D. Reddy P, et al. Biol Blood Marrow Transplant. 2012 Jan;18(1 Suppl):S17-26. doi: 10.1016/j.bbmt.2011.10.034. Biol Blood Marrow Transplant. 2012. PMID: 22226102 Free PMC article. Review. No abstract available.
In vitro-established alloantigen-specific CD8+ CTLs mediate graft-versus-tumor activity in the absence of graft-versus-host disease.
Hartmann N, Leithäuser F, Albers C, Duyster J, Möller P, Debatin KM, Strauss G. Hartmann N, et al. Leukemia. 2011 May;25(5):848-55. doi: 10.1038/leu.2011.16. Epub 2011 Feb 18. Leukemia. 2011. PMID: 21331071
[Preventive measures for graft-versus-host disease].
Teshima T. Teshima T. Nihon Naika Gakkai Zasshi. 2005 Jul 10;94(7):1356-61. doi: 10.2169/naika.94.1356. Nihon Naika Gakkai Zasshi. 2005. PMID: 16097592 Review. Japanese. No abstract available.