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Review
. 2003 Feb;81(2):117-31.
doi: 10.1016/s0079-6107(02)00049-4.

Renal aquaporin water channels: from molecules to human disease

Robert W Schrier  1 , Melissa A Cadnapaphornchai
Affiliations
Free article
Review

Renal aquaporin water channels: from molecules to human disease

Robert W Schrier et al. Prog Biophys Mol Biol. 2003 Feb.
Free article

Abstract

Following the discovery of the aquaporin-1 water channel in 1991, molecular techniques have been developed to examine the roles of renal aquaporins-1, -2, -3, and -4 in disorders of water balance. This article reviews current knowledge regarding aquaporin function and dysfunction in water-losing and water-retaining states.

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