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. 2003 Jan;69(1):75-7.
doi: 10.1055/s-2003-37042.

The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare

Sanae El Bardai, Nicole Morel, Maurice Wibo, Nicolas Fabre, Gabriel Llabres, Badiaa Lyoussi, Joëlle Quetin-Leclercq

The vasorelaxant activity of marrubenol and marrubiin from Marrubium vulgare

Sanae El Bardai et al. Planta Med. 2003 Jan.

Abstract

Crude extracts of the aerial parts of Marrubium vulgare show a potent in vitro inhibition of KCl-induced contraction of rat aorta. Bio-guided fractionations, spectroscopic analysis and chemical derivatization revealed the furanic labdane diterpenes marrubenol and marrubiin as the most active compounds.

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