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Review
. 2003 Feb;111(3):318-21.
doi: 10.1172/JCI17744.

Endothelial lipase: direct evidence for a role in HDL metabolism

Affiliations
Review

Endothelial lipase: direct evidence for a role in HDL metabolism

Jonathan C Cohen. J Clin Invest. 2003 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Sequence alignment of lipoprotein lipase (lpl), hepatic lipase (hl), and endothelial lipase (el) from human (h) and pufferfish Takifugu rubripes (f). Amino acids that are identical in all three genes in both species are shaded in grey. The serine, aspartic acid, and histidine resides of the catalytic triad, as well as the lipase motif (GXSXG) are boxed. The conserved cysteine residues are denoted with closed circles. The lid domain is indicated with a single line, and the conserved heparin-binding region (BBXB) is indicated with a double line.

Comment on

References

    1. 1993. National cholesterol education program. Second report of the expert panel on detection, evaluation and treatment of high blood cholesterol in adults. National Institutes of Health. Bethesda, Maryland, USA. IV:4–IV:5.
    1. Miller GJ, Miller NE. Plasma-high-density-lipoprotein concentration and development of ischaemic heart-disease. Lancet. 1975;1:16–19. - PubMed
    1. Gordon T, Castelli WP, Hjortland MC, Kannel WB, Dawber TR. High density lipoprotein as a protective factor against coronary heart disease. The Framingham Study. Am. J. Med. 1977;62:707–714. - PubMed
    1. Wiklund O, et al. Alpha-lipoprotein cholesterol concentration in relation to subsequent myocardial infarction in hypercholesterolemic men. Atherosclerosis. 1980;37:47–53. - PubMed
    1. Frick MH, et al. Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. N. Engl. J. Med. 1987;317:1237–1245. - PubMed