[Sézary's syndrome. Case report]

Abstract

A patient with Sézary syndrome is presented. The symptoms persisted for 5 years when a sudden involvement of internal organs led to the death of the patient. Much evidence indicates that the Sézary syndrome is a special form of mycosis fungoides with erythroderma and a constant release of atypical cells into the blood. The nature of the Sézary cell has not yet been clearly elucidated. Cytogenetic and immunological findings identified the Sézary cell as an abnormal T-lymphocyte whereas cytochemical data support the concept of the presence of different atypical cell populations with lymphocytic respectively monocytic character.