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Review
. 2003 Feb 6;37(3):370-2.
doi: 10.1016/s0896-6273(03)00060-6.

It takes two to tango, but three to ISA

Paco S Herson  1 , John P Adelman
Affiliations
Free article
Review

It takes two to tango, but three to ISA

Paco S Herson et al. Neuron. .
Free article

Abstract

Rapidly inactivating A-type potassium channels are important determinants of firing frequency in many excitable cells. Nadal et al. (in this issue of Neuron) purified A-type potassium (I(SA)) channels from rat cerebellum and identified a novel beta subunit. This protein, DPPX, associates with the pore-forming subunits and endows previously elusive kinetic properties on A-type channels formed from cloned subunits.

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