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. 2003 Feb;142(2):197-9.
doi: 10.1067/mpd.2003.93.

Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis

Cara L Mack  1 , Riccardo A Superina, Peter F Whitington
Affiliations

Surgical restoration of portal flow corrects procoagulant and anticoagulant deficiencies associated with extrahepatic portal vein thrombosis

Cara L Mack et al. J Pediatr. 2003 Feb.

Abstract

Extrahepatic portal vein thrombosis (EHPVT) is associated with abnormal circulating procoagulants and anticoagulants. Eleven children with EHPVT and abnormal coagulation factors underwent a mesenterico-left portal vein bypass to restore portal flow. Coagulation factors had returned to normal by one year. The data suggest that portal venous flow is essential for maintaining normal coagulation.

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