Inflammation and Alzheimer's disease

Abstract

Alzheimer's disease (AD) is classified mainly as a neurodegenerative disease. Recent research, however, has shown that inflammatory mechanisms are also associated with AD and that they could have a role in contributing to the pathogenesis of this disease. The evidence is based on histopathological brain studies, laboratory studies of peripheral inflammation and the fact that certain anti-inflammatory drugs could modify the course of AD. There is wide scope for further research using anti-inflammatory therapies in the prevention/treatment of AD, thereby reducing the burden of this widely prevalent condition in the community.