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. 2003 Mar;89(3):255-7.
doi: 10.1136/heart.89.3.255.

A "natural experiment" in cardiovascular epidemiology in the early 21st century

A Sekikawa  1 , B Y Horiuchi, D Edmundowicz, H Ueshima, J D Curb, K Sutton-Tyrrell, T Okamura, T Kadowaki, A Kashiwagi, K Mitsunami, K Murata, Y Nakamura, B L Rodriguez, L H Kuller
Affiliations

A "natural experiment" in cardiovascular epidemiology in the early 21st century

A Sekikawa et al. Heart. 2003 Mar.

Abstract

Despite similar traditional risk factors, morbidity and mortality rates from coronary heart disease in western and non-western cohorts remain substantially different. Careful study of such cohorts may help identify novel risk factors for CHD, and contribute to the formulation of new preventive strategies

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Figures

Figure 1
Figure 1
Mortality from coronary heart disease (CHD, black bars), heart failure (white bars), and diseases of the heart other than CHD or heart failure (grey bars) among men aged 35–44. (A) Whites in the USA, (B) Japanese Americans in Hawaii, and (C) Japanese in Japan. Data were average mortality from 1990 to 1998 for whites in the USA and Japanese Americans in Hawaii, and from 1990 to 1997 for Japanese men in Japan. International classification of diseases (ICD) codes (9th revision) for CHD, HF, and diseases of the heart other than CHD and heart failure are 410–414, 428, and 390–429, respectively. Japan introduced the 10th revision of ICD from 1995, and the corresponding codes were used. Data were from the CDC Wonder for Caucasians in the US, Hawaii Department of Health for Japanese Americans in Hawaii, and from the Ministry of Health and Welfare in Japan for Japanese men in Japan.
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