Hair cell regeneration: winging our way towards a sound future
- PMID: 12593990
- DOI: 10.1016/s0959-4388(03)00018-7
Hair cell regeneration: winging our way towards a sound future
Abstract
The discovery of hair cell regeneration in the inner ear of birds provides new optimism that there may be a treatment for hearing and balance disorders. In this review we describe the process of hair cell regeneration in birds; including restoration of function, recovery of perception and what is currently known about molecular events, such as growth factors and signalling systems. We examine some of the key recent findings in both birds and mammals.
Similar articles
-
Mammalian auditory hair cell regeneration/repair and protection: a review and future directions.Ear Nose Throat J. 1998 Apr;77(4):276, 280, 282-5. Ear Nose Throat J. 1998. PMID: 9581394 Review.
-
[The influence of glucocorticoids on the view of chicken's inner ear damage after exposure to wide-band-noise].Otolaryngol Pol. 2006;60(4):587-92. Otolaryngol Pol. 2006. PMID: 17152814 Polish.
-
Functional recovery in the avian ear after hair cell regeneration.Audiol Neurootol. 1999 Nov-Dec;4(6):286-302. doi: 10.1159/000013853. Audiol Neurootol. 1999. PMID: 10516389 Review.
-
Regeneration after tall hair cell damage following severe acoustic trauma in adult pigeons: correlation between cochlear morphology, compound action potential responses and single fiber properties in single animals.Hear Res. 1996 Dec 1;102(1-2):133-54. doi: 10.1016/s0378-5955(96)00155-4. Hear Res. 1996. PMID: 8951458
-
[Hair cell regeneration in the inner ear of birds and mammals].HNO. 1995 May;43(5):269-70. HNO. 1995. PMID: 7607908 German. No abstract available.
Cited by
-
Avian auditory hair cell regeneration is accompanied by JAK/STAT-dependent expression of immune-related genes in supporting cells.Development. 2022 Apr 15;149(8):dev200113. doi: 10.1242/dev.200113. Epub 2022 May 3. Development. 2022. PMID: 35420675 Free PMC article.
-
Activin potentiates proliferation in mature avian auditory sensory epithelium.J Neurosci. 2010 Jan 13;30(2):478-90. doi: 10.1523/JNEUROSCI.5154-09.2010. J Neurosci. 2010. PMID: 20071511 Free PMC article.
-
The differentiation of Lgr5+ progenitor cells on nanostructures of self-assembled silica beads.PLoS One. 2024 Jul 12;19(7):e0304809. doi: 10.1371/journal.pone.0304809. eCollection 2024. PLoS One. 2024. PMID: 38995923 Free PMC article.
-
Spontaneous Hair Cell Regeneration Is Prevented by Increased Notch Signaling in Supporting Cells.Front Cell Neurosci. 2018 May 4;12:120. doi: 10.3389/fncel.2018.00120. eCollection 2018. Front Cell Neurosci. 2018. PMID: 29780306 Free PMC article.
-
Notch signaling regulates regeneration in the avian retina.Dev Biol. 2007 Dec 1;312(1):300-11. doi: 10.1016/j.ydbio.2007.09.046. Epub 2007 Sep 29. Dev Biol. 2007. PMID: 18028900 Free PMC article.
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources