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. 1975 Aug 8;83(4):261-7.
doi: 10.1007/BF00573012.

Ultrastructure of ovarian teratomas in LT mice

I Damjanov, V Katić, L C Stevens

Ultrastructure of ovarian teratomas in LT mice

I Damjanov et al. Z Krebsforsch Klin Onkol Cancer Res Clin Oncol. .

Abstract

Stem cells of these tumors formed nests consisting of undifferentiated embryonic cells in the center with more differentiated cells towards the periphery. A type viral particles were seen in the cisternae of rough endoplasmic reticulum. Ultrastructurally the stem cells of ovarian teratomas did not differ from stem cells of testicular or embryo-derived teratomas. They were however distinct from the cleavage stage embryonic cells and/or the unfertilized ovum, they stemmed from. They correspond both cytologically and developmentally to ectodermal embryonic cells from the egg-cylinder, the most advanced developmental stage of parthenotes observed previously in the ovary of LT mice.

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