[An immunohistochemical study on the distribution in organs in cases with morphine poisoning]
- PMID: 12596579
[An immunohistochemical study on the distribution in organs in cases with morphine poisoning]
Abstract
Objective: To investigate the distribution of mophine in organs in cases with morphine poisioning to select ideal organs for immunohistochemical derection.
Methods: Localization and half quantitation of morphine in the brain, the kidney, the heart, and the liver were studied in 8 cases with morphine poisoning by immunohistochemical SP method.
Results: Morphine was mainly detected in the cytoplasm of certain parenchymal cells of the organs. The distribution varied greatly with different cases and organs. In the brain and kidney, morphine-positive cells could be easily found.
Conclusion: The kidney and brain may be the ideal organs for sampling in suspected morphine poisoning cases with.
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